AIP Publishing LLC
AIP Publishing LLC
  • pubs.aip.org
  • AIP
  • AIP China
  • University Science Books
  • Resources
    • Researchers
    • Librarians
    • Publishing Partners
    • Topical Portfolios
    • Commercial Partners
  • Publications

    Find the Right Journal

    Explore the AIP Publishing collection by title, topic, impact, citations, and more.
    Browse Journals

    Latest Content

    Read about the newest discoveries and developments in the physical sciences.
    See What's New

    Publications

    • Journals
    • Books
    • Physics Today
    • AIP Conference Proceedings
    • Scilight
    • Find the Right Journal
    • Latest Content
  • About
    • About Us
    • News and Announcements
    • Careers
    • Events
    • Leadership
    • Contact
  • pubs.aip.org
  • AIP
  • AIP China
  • University Science Books

Exploring Dynamics of Blood Flow in Vascular, Atherosclerotic Diseases

  • May 10, 2022
  • Physics of Fluids
  • News
Share:

From the Journal: Physics of Fluids

WASHINGTON, May 10, 2022 – Medical interventions, such as improving diet, lowering blood lipids, or controlling blood pressure and blood sugar, can only do so much when it comes to treating atherosclerotic disease. Is it possible to make earlier predictions for risk factors for plaque formation within the carotid arteries via characteristics of vascular structure and the dynamics of blood flow before the disease progresses?

3D reconstruction of a carotid artery stenosis vessel, and diameter and flow rate at the blood vessel inlet and outlet (left) and 3D printed simulation model (right). CREDIT: Zhiyong Song, Pengrui Zhu, Lianzhi Yang, Zhaohui Liu, Hua Li, and Weiyao Zhu
3D reconstruction of a carotid artery stenosis vessel, and diameter and flow rate at the blood vessel inlet and outlet (left) and 3D printed simulation model (right). CREDIT: Zhiyong Song, Pengrui Zhu, Lianzhi Yang, Zhaohui Liu, Hua Li, and Weiyao Zhu

In Physics of Fluids, from AIP Publishing, researchers in China present clinicians with information about the risk factors for atherosclerotic plaque formation from a mechanical point of view. The scientists are exploring whether it is possible to screen and intervene early for people at risk for atherosclerotic disease from the perspective of hemodynamics, using color Doppler ultrasound, coronary computed tomography angiography, and other screenings.

“Carotid endarterectomy and carotid artery stenting are the main methods for treatment of carotid artery stenosis,” said Zhiyong Song, from the University of Science and Technology Beijing. “Changes of postoperative vascular structure and fluid mechanics are important for restenosis, so determining how to minimize risk factors of postoperative flow is important for improving the therapeutic effect.”

A multipoint, noncontact laser flow measurement method called microparticle image velocimetry (Micro-PIV) was used by the researchers, something they said has been continuously improved during the past few decades and exceeds the limitations of single-point measurement technologies.

“It could record speed distribution information on a large number of spatial points within the same transient state to provide rich spatial structure of flow field and flow characteristics,” said Song.

The researchers discovered a significant gap between their study and the clinical method in terms of wall shear strength calculation, which could lead to confusion about the physiological mechanism.

“Based on the plateau-like distribution of the velocity field at the central carotid stenosis location shown by Micro-PIV and simulations, the current clinical estimation method of wall shear stress at the stenosis location could result in a difference of up to 60%,” Song said.

The group’s hemodynamic study of carotid atherosclerotic plaque has important clinical significance for understanding the formation and development mechanism of atherosclerotic disease, improving surgical treatment technology, and researching and developing future medical devices.

###

For more information:
Larry Frum
media@aip.org
301-209-3090

Article Title

Study on the radial sectional velocity distribution and wall shear stress associated with carotid artery stenosis

Authors

Zhiyong Song, Pengrui Zhu, Lianzhi Yang, Zhaohui Liu, Hua Li, and Weiyao Zhu

Author Affiliations

University of Science and Technology Beijing and Hainan General Hospital


Physics of Fluids

Physics of Fluids is devoted to the publication of original theoretical, computational, and experimental contributions to the dynamics of gases, liquids, and complex or multiphase fluids.

http://pof.aip.org

Share:
  • Wearable, Inexpensive Robotic Sleeve for Lymphedema Treatment
  • At Home, Do-It-Yourself Fluid Mechanics

Keep Up With AIP Publishing

Sign up for the AIP newsletter to receive the latest news and information from AIP Publishing.
Sign Up

AIP PUBLISHING

1305 Walt Whitman Road,
Suite 110
Melville, NY 11747
(516) 576-2200

Resources

  • Researchers
  • Librarians
  • Publishing Partners
  • Commercial Partners

About

  • About Us
  • Careers 
  • Leadership

Support

  • Contact Us
  • Terms Of Use
  • Privacy Policy

© 2025 AIP Publishing LLC
  • 𝕏